Saturday, 18 March 2017

Book Review: Herbs & Nutrients for Neurological Disorders; Treatment Strategies for Alzhiemer’s, Parkinson’s, Stroke, Multiple Sclerosis, Migraine & Seizures. By Sidney J. Kurn, M.D. and Sheryl Shook, Ph. D.


This Book Review first appeared in New Dawn Magazine issue 159, November-December 2016. © Brett Lothian.




Book Review:  
Herbs & Nutrients for Neurological Disorders: Treatment Strategies for Alzhiemer’s, Parkinson’s, Stroke, Multiple Sclerosis, Migraine & Seizures.  
By Sidney J. Kurn, M.D. and Sheryl Shook, Ph. D.


Herbs and Nutrients for Neurological Disorders is an outstanding and much needed book that deals with some of the greatest blights of our modern world and lifestyle. This thoroughly researched and clinically tested manual for treating neurological disorders is a must have for any practitioner working in health care or anyone that has been touched by these horrific and debilitating illnesses, which is far too many of us. Step by step, the authors take the reader through the important factors these disorders have in common, the importance of sleep, to the possible causes and contributing factors to these illnesses and to the herbal and nutritional treatments that have been shown to have exciting results. This book highlights once again how important diet, lifestyle and making informed choices are in the maintenance of good health and well being in an increasingly polluted and poisonous world.



Firstly, the authors provide a guide for how to use this book, explaining how the book was initially compiled from lectures and handouts introducing practitioners, patients and their families to the judicious use of supplements in various neurological disorders and how each chapter arose in slightly different contexts and varied in terms of the description of the disorder and the relationship of the herbs and nutrients to the underlying disease mechanisms. This variety reflects the enthusiasm of the authors for certain topics, particularly regarding disease mechanisms, prompted by new discoveries in neurological science. The book has been designed so that it is useful for the reader to firstly read the summary section of each chapter and then go back and read the detailed science behind the treatment options, or you can just read it cover to cover like I did.



Next, importantly the authors discuss the factors all six disorders have in common, the contributing factors , such as inflammation, free radicals, MSG, Aspartame, toxic pesticides, environmental pollutants, heavy metals, mitochondrial dysfunction, genetics, epigenitics, and treatments such as nutrients, cannabinoids and the microbiome. These are problems all of us face in our modern world which has unfortunately, largely shifted the environmental debate away from toxins, pollutants and a lack of basic nutrients in our top soil, to the non toxic and environmentally beneficial carbon, in the climate change debate.



Sleep is discussed as it’s importance in all aspects of health is paramount and an important factor in the development and treatment of these neurological disorders. Numerous recognised sleep tests are provided for the reader to gauge their levels of healthy sleep and the authors also provide techniques and practices to improve sleep length and quality. Far too many of us do not get enough quality sleep in our hustle and bustle, time poor lives at great risk to our health and future prospects of developing a neurological disorder. It is a society wide issue that certainly needs to be addressed for our worlds common health.



Each chapter focusing on the six neurological disorders breaks down the diagnosis, current treatments, causes, factors involved, dietary considerations, supplementation and herbal treatments. Some of the technical language and medical concepts can be a little hard to follow for the uninitiated, but the basic jist can always be understood. The authors summarise each chapter in easy to understand language and the treatment protocols are very easy to follow. Many of the beneficial herbs such as turmeric, gingko biloba discussed and other supplements recommended are easily obtainable for most people. Marijuana which is recommended in almost all cases obviously will require some much needed and long over due law reform before it is available in this country medicinally, well, legally anyway.



The authors offer Herbs and Nutrients for Neurological Disorders as an introduction to the vast naturopathic literature regarding these common neurological disorders. Much of this literature appears in mainstream, peer reviewed speciality journals, yet the implications remain largely un-integrated into standard medical practice. This is a loss for the patient, the practitioner and the practice of medicine as a whole. The patient loses the benefit of simple, inexpensive remedies and medicine becomes increasingly technical, expensive and unavailable to all. A truly integrated medicine cannot afford to ignore any potential treatment because of financial, political or paradigmatic reasons. We all lose in the end, encumbered by an increasingly expensive and less effective system of medicine.



The authors hope, that this book will help clear the way and empower the reader in pursuit of his or her better health. It certainly gave me a far greater understanding of these neurological disorders, how they are caused and what I can do to help prevent and treat them. Highly recommended for health practitioners, neurological disorder sufferers, friends and families and anyone interested in maintaining good neurological health.



By Brett Lothian

Book Review: Dreaming Wide Awake; Lucid Dreaming, Shamanic Healing and Psychedelics. By David Jay Brown




This book review first appeared in New Dawn Magazine issue 160 January - February  2017.
© Brett Lothian.



Book Review
Dreaming Wide Awake: Lucid Dreaming, Shamanic Healing and Psychedelics.
By David Jay Brown

Dreaming Wide Awake is an outstanding and in depth guide to Lucid Dreaming, altered states of consciousness and the potentials that they contain for healing, psychic development and spiritual awakening. Combining the latest scientific research, ancient wisdom and personal experience, the author takes us on a fantastic voyage through the realms of the conscious unconscious, exploring the many archetypes and spiritual dimensions that lay just beyond our ordinary perception of reality. Not only will this book give you a fascinating insight in to the dreaming mind, out of body experiences and alternate realities, but it will teach you the techniques that you need to explore them yourself first hand. 

The author is extremely well researched and his easily accessible style makes this a great book for the beginner, whilst covering such a broad range of subject matter that it will keep even the most experienced inner traveller turning the page. Coming from a western scientific approach, the book manages to remain balanced and grounded, whilst discussing a range of varying perspectives on the lucid dreaming experience and other related altered states of consciousness. Drawing upon both ancient and modern schools of thought and incorporating various aids such as plant allies, psychedelics and modern technology, the author gives us a true in depth modern manual to an ancient mystic art.

Dreaming Wide Awake is particularly helpful for those suffering from post-traumatic stress, night terrors and recurring nightmares, as it teaches us how to take control of our dreams, to change them and how to use lucid dreaming to heal the past traumas that lie buried deep within our subconscious. Lucid dreaming offers a safe, effective and outright exhilarating alternative therapeutic option for those suffering the torment of revisiting their worst nightmares on a nightly basis. With this book you will even learn how to develop super powers, from soaring high above the clouds like an eagle to shape-shifting and becoming one, if you so desire in the dream realm. Learning this ability to take control of your reality in waking dreams, also transfers over into waking reality, effectively training you to be more confident, adaptable and successful in making your hopes and dreams become actual reality. 



This book will be of particular interest to the psychonaut, the mystic and the spiritual seeker. The author skilfully takes us through the parallels and similarities between Dreaming Wide Awake, the psychedelic experience, shamanic healing and visionary states of consciousness, discussing everything from archetypes, spirits and disembodied entities (and how to communicate with them) to psychic phenomena, shared experiences and alternate realities. For those that are new to journeying beyond ordinary reality and wish to develop their confidence and abilities, to contact someone on the other side or simply to vision quest, Dreaming Wide Awake provides a fantastic way to safely train yourself to have better control and to maintain your intention when in an altered state of consciousness, whether lucid dreaming or in a shamanic healing ceremony or sweat lodge vision quest.

Of particular interest to me is the use of technology to enhance lucid dreaming and other altered states of consciousness. I think this is a vastly under studied area (outside of the MKUltra program that is) that holds tremendous potential for allowing everyone access to the other realms outside of ordinary reality. The author takes us through his experimentation with various devices and aids, bravely plunging into the depths of his own mind in what are truly fascinating experiences, revealing the power over the mind and perception that technology can have. Whilst obviously there is the potential for these types of technologies to be used for nefarious means by our friends at the various alphabet agencies, they also have the potential to be used for great good and healing when used by the practitioner at home. 

Dreaming Wide Awake will plunge you headlong into the very nature of reality itself and forces us to question our widely accepted notions about existence, our place in the universe and our power to shape reality. Whilst always staying grounded, evidence based and easy to understand, David Jay Brown has created a modern masterpiece in psychonautical exploration. Ultimately, this is a book about healing, seeking our true nature and spiritual empowerment. If these are subjects of interest to you, you will not be disappointed in Dreaming Wide Awake, an instant classic.

By Brett Lothian

Blushwood: The Endangered Australian Native Cancer Killer



This article first appeared in New Dawn Special Issue Volume 10 Number 5 October 2016. © Brett Lothian.


Blushwood: The Endangered Australian Native Cancer Killer

An amazing discovery has been made in the Atherton Table lands region (near Cairns) of tropical far North Queensland, a family of shrubs and small trees thats flowers, seeds, leaves, roots, wood and bark contain a compound that kills cancerous tumors in a matter of mere days, with no long term side effects. Plants in the Fontainea family, especially Fontainea picrosperma/Hylandia dockrillii, and Fontainea venosa, more commonly known as the Blushwood tree or shrub, has been shown in animal studies, as well as in initial human studies, to be remarkably effective against solid tumors such as melanoma, head, neck and breast cancers, some of the biggest killers in the world each year. The problem is, these much needed miracle plants are largely endangered in the wild, with only a few small pockets being known of for some, and the only propagation of these amazing plants is currently under the control of the pharmaceutical industry.

The initial discovery was made by Dr Victoria Gordon and Dr Paul Reddell of EcoBiotics in 2006, who observed that marsupials find the seed of Fontainea picrosperma/Hylandia dockrillii unpalatable due to an inflammatory chemical present in reasonably high concentrations. Gordon and Reddell sent off a batch of crushed kernels to a commercial lab in Sydney to investigate any possibly useful compounds, finding powerful anti cancer properties in a compound named EBC-46 and powerful wound healing properties in a compound named WH-1. Scientists at the QIMR Berghofer Medical Research Institute in Brisbane, led by Dr Glen Boyle tested the compound EBC-46, on a tumour cell line and were astonished by its effectiveness. When applied to a laboratory mouse implanted with human skin cancer, the melanoma turned red and purple, then melted before their eyes.



Since then, the drug has been tried experimentally on various animals that were diagnosed by veterinarians and given a poor prognosis, most being considered candidates for euthanasia prior to participating in the study.  Dogs, cats, horses, pigs, sheep, ferrets, guinea pigs, goanna, birds, even the endangered Tasmanian devil were tested, amazingly these animals that had been on death’s door prior to the study had their melanoma tumors disappear after treatment in the lab by Dr. Boyle and his team of scientists at QIMR, obliterating tumors in nearly all of them. Dr Boyle stated that “In most cases the single injection treatment caused the loss of viability of cancer cells within four hours, and ultimately destroyed the tumors.”

Herein lies the beauty of the compound, or at least in how it has been seen to work in animals and the early human clinical trials, in most cases, a set of five or six injections does the trick, but a follow up course can be required. Dr. Boyle says EBC-46 works in part by triggering a cellular response which effectively cuts off the blood supply to the tumor. “In more than 70 per cent of pre clinical cases, the response and cure was long term and enduring, with very little relapse over a period of 12 months.” 

Evidently, the Blushwood shrubs amazing healing properties do not stop there, it also kicks up the bodies natural healing response, healing the wound with soft, new skin and reduced scarring.“Some of the wound healing we’ve witnessed so far in pilot studies with pet dogs has been remarkable. These animals had chronic non-healing wounds that weren’t responding to current standard of care treatments before being treated with our new compound,” said Dr Gordon. “Based on these extremely encouraging results we are now moving to more fully evaluate the prospect of developing this drug as a treatment for both chronic and acute wounds. Wound healing is a large market ($14 billion annually in the USA alone) where there is significant demand for new and effective products for application in both human and veterinary medicine,” said Dr Gordon.

Of the 344 animals treated to date  about two thirds of them dogs 78 per cent ended up cancer free or with tumor mass reduced by more than half. Fewer than nine per cent failed to respond. Bone cancers and highly fibrous tumors have so far proven to be resistant, possibly because not enough EBC-46 can penetrate into the cancer. EcoBiotics is also progressing with its plans in international veterinary cancer markets, following approval from the US Centre for Veterinary Medicine for further studies on the treatment of canine mast cell tumours with EBC-46. This approved study will involve 10 investigative sites and 120 cases for the treatment of canine tumours, and would be the final clinical step to use of the product in the US for canine mast cell tumors. Dr Gordon said once the study was completed, the company would seek regulatory approval from the Australian Pesticides and Veterinary Medicines Authority to make the drug commercially available to the domestic vet market.

Multi-centre human Clinical Phase I/II trial, which started in 2015, are showing encouraging results. According to Dr Gordon, the study has now treated eight human patients. “This study is primarily being undertaken to examine the safety of EBC-46,” Dr Gordon said. “The drug has been well tolerated by all patients treated. In addition, sound evidence of efficacy has also been noted in tumors of all the patients treated. This is shown by the appearance of bruising and initial tumor breakdown on the section of the tumor treated. This response in humans is very similar to what has been seen in the successful veterinary studies with EBC-46 where full tumor destruction is noted.” Tumor types in the human trial treated to date are melanoma, squamous cell carcinoma, basal cell carcinoma and breast adenocarcinoma. 

  
Denise Powell, one of the cancer sufferers who has joined the trial in Queensland, had a tumor in her armpit that was getting progressively worse, “My cancer surgeon said, ‘I can take that one out, if you get any more you might lose an arm.” Doctors injected the trial drug EBC-46 directly into Denises tumor, “In less than 20 minutes the tumor had gone purple then black,” Denise said. “Then within a couple of days the tumor just kind of shrivelled up and died”. Dr Gordon said none of the patients, who were treated at hospitals in Brisbane, Sydney, Melbourne and Adelaide, showed any negative side effects from the drug. “These initial results, that are clearly showing potential for a good safety profile for the drug combined with early signs of efficacy in a range of tumor types, are very encouraging,” said Dr Gordon. “The exciting thing is the drugs are responding in exactly the same way in tumors in cats, dogs and horses. It’s proving our theory that it’s not species specific, and it’s not tumor specific either, because it’s actually working in a range of tumors.”  She expected the drug, once it had been trialled on at least 11 more human patients, would become commercially available within the next four years. Encouraging to say the least.

What is not encouraging however is the threatened status of these endangered plants and the way that this discovery has been reported so far in the mainstream media. Whilst this amazing discovery has garnered a small amount of press coverage, in every article in the mainstream media I could find, the only plant mentioned to be containing EBC-46 and WH-1 is Hylandia dockrillii, the Blushwood shrub. None of them mention that Hylandia dockrilli is synonymous with Fontainea picrosperma or that the initial study identified Fontainea pancheri, Fontainea australis, Fontainea borealis, Fontainea fugax, Fontainea oraria, Fontainea rostrata, Fontainea subpapuana and Fontainea venosa as containing EBC-46 and WH-1. With Fontainea picrosperma, or Hylandia dockrillii and Fontainea venosa found to be the most useful. Also they do not mention that numerous other compounds discovered in the fontainea genus also show remarkable promise in regards to killing cancer as well as treating other ailments. Now, this may have been simple over site, the writers editing down to fit word counts or perhaps an attempt keep the compounds EBC-46, WH-1 and the Blushwood shrubs relatively obscure from the public, therefore protecting the discovery for the‘big pharma’ industry. Whilst EcoBiotics and it’s subsidiary QBiotics (which is developing these compounds), are not ‘big pharma’ in themselves, being a small Queensland company, they will have to find a lot of funding if they are ever to get these compounds to market, which means selling the rights to the compound to the big boys.

If EBC-46 gets through to Clinical Phase III, the critical proving trial that generally involves thousands of patients around the world (which it appears so far that it will, with flying colours), it will have burned through all of the cash EcoBiotics have raised, and more. The majority of their 1200 shareholders are mums and dads who have kicked in as little as $1500; the biggest single outside stake in the unlisted company is $1 million. This is more by accident than design. Dr Gordon initially did the rounds of venture finance providers but was rebuffed; prove it up and come back to us, the money men told her.

The expense of getting a drug to market is staggering, which helps explain why so few get through in Australia. Picato, a rare success story, had $130 million ploughed into it by Danish outfit LEO Pharma before being registered by the Therapeutic Goods Administration last year. In a small pond, Australia’s CSL is the nearest thing there is to a big local fish. Yet to meet the development cost it had to license the international rights of Gardasil - the controversial cervical cancer vaccine pioneered by 2006 Australian of the Year Ian Frazer - to US giant Merck. Dr Gordon estimates that EBC-46 will require north of $600 million to be made into a medicine - completely out of their league. She and Reddell have structured the company so that the subsidiary, QBiotics, contains the intellectual property and could be peeled off for outright sale or a stock market float. Which is most likely what will end up happening seeing the extraordinary promise of the Blushwood extracts EBC-46 and WH-1.

The rights to these compounds ECB-46 and WH-1 may be owned by Ecobiotics through their subsidiary QBiotics, but they do not own the plants they are derived from. They certainly do deserve credit and to do extremely well out of their discovery and hard work. I in no way wish to disparage the truly fantastic work Dr Victoria Gordon and Dr Paul Reddell of EcoBiotics have done and genuinely do hope that they get these compounds to the market, as they are sorely needed no matter how it happens. What I do not want to see however is only ‘big pharma’ growing these plants and controlling access to them. This is where I hope the intrepid readers of New Dawn magazine and Tricho Serious Ethnobotany can help out.



I would like to call upon the New Dawn and Tricho Serious Ethnobotany readers in the areas where these plants grow, to actively hunt down these plants in habitat and procure seed and or cuttings, so that these amazing life saving plants themselves can be saved, for all of us. The nine currently known species of Fontainea grow naturally in Queensland and New South Wales (6 sp), New Caledonia and Vanuatu (1 sp), and Papua New Guinea (2 sp). Some species are commonly named Blushwood, but not all and fruit from spring through to autumn. One species, Fontainea oraria, the coast Fontainea, is known only from 10 living plants growing on private property near Lennox Head in northern New South Wales. Its status is critically endangered. Locating the two most promising species Fontainea picrosperma/Hylandia dockrillii and Fontainea venosa should be relatively easy with Fontainea picrosperma/hylandia dockrillii being located in and around the Atherton Tablands near Cairns and Fontainea venosa being located in South East Queensland around the Gympie area. Exact habitat locations for Fontainea picrosperma/hylandia dockrillii can be found in the resources section following this article.

It should be noted that experimentation with any parts of these plants is potentially dangerous, although the researchers are adamant that the drug has potential to be used internally as well as the current external treatments, the necessary work is yet to be done. “The sting in the tail is that it has to be put on the outside of the body,” explains QIMR Berghofer director and CEO Frank Gannon. “It is highly toxic if it gets into the body unless it can be controlled”. Also there has been absolutely no study on what a raw plant extract would do, if anything at all and may be very dangerous if ingested considering the inflammatory response it triggers, which first led to its discovery.

In conclusion, these endangered miracle plants need us to protect them, spread them around and study them. We simply must not allow the only access to these plants to be through a big pharmaceutical company that cares only for profit, not people. The fact that these endangered plants have proven to be so effective and relatively safe, worries me greatly. We run the risk of having this amazing discovery being simply bought and shelved, as cures are not as profitable as “treatments”, such as the ineffective but lucrative chemotherapy “treatments” that slowly milk your wallet before killing you. We have pushed these plants to the brink of extinction through habitat encroachment, whilst the disease they cure is ravaging our population worldwide, maybe we don’t deserve such miracle plants such as the Blushwood shrubs, considering our treatment of the Earth and her bounty, but it is not too late to put people before profit.

If you are able to procure seed or live plants please feel free to contact Brett at bretloth@gmail.com.

About the author: Brett Lothian is an Australian author, professional arborist, market gardener and ethnobotanist. He is the author of the Tricho Serious Ethnobotany blog and creator of the Trichocereus Cacti Appreciation group, the Peyote Appreciation group and the Ethnobotany Appreciation group on facebook.



Resources:

Blushwood vs Cancer By Rex Research
http://rexresearch.com/blushwood/gordon.htm

Fontainea
http://america.pink/fontainea_1577157.html

EBC-46
http://america.pink/ebc_1346352.html

Blushwood Tree & Shrub
http://blushwood.com/index.htm

Blushwood Tree Locations
http://blushwood.com/blushwood_tree_locations.htm

How Blushwood Berries Can Destroy Cancer Cells Almost Instantly by Jenny Hills
http://www.healthyandnaturalworld.com/blushwood-berries-can-destroy-cancer-cells-almost-instantly/

QBiotics set for cancer trials and wound healing investigations
http://www.palin.com.au/news-and-media/qbiotics-set-for-cancer-trials-and-wound-healing-investigations

Anti-cancer drug discovered in rainforest successfully tested on humans by Daniel Bateman
http://www.cairnspost.com.au/lifestyle/anticancer-drug-discovered-in-rainforest-successfully-tested-on-humans/news-story/9b6da3a28fb5efa23e0a01b5e40e63b5

'Cancer-fighting' berry in Australian rainforests
https://au.news.yahoo.com/thewest/a/32374777/cancer-fighting-berry-in-australian-rainforests/#page1

Compound derived from Australian rainforest progresses in human trials
http://biotechdispatch.com.au/compound-derived-from-australian-rainforest-progresses-in-human-trials/

Have Victoria Gordon and Paul Reddell found a new weapon against cancer with blushwood? http://www.theaustralian.com.au/life/weekend-australian-magazine/have-victoria-gordon-and-paul-reddell-found-a-new-weapon-against-cancer-with-blushwood/story-e6frg8h6-1226877070142

Fontainea
https://en.wikipedia.org/wiki/Fontainea